SH2B3 polyclonal antibody
产品名称： SH2B3 polyclonal antibody
英文名称： SH2B3 polyclonal antibody
产品编号： PAB6669
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of SH2B3.
- Immunogen:
- A synthetic peptide corresponding to human SH2B3.
- Sequence:
- NGPALQPSSPC
- Host:
- Goat
- Theoretical MW (kDa):
- 63.2
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:64000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Cloning and characterization of human Lnk, an adaptor protein with pleckstrin homology and Src homology 2 domains that can inhibit T cell activation.
Li Y, He X, Schembri-King J, Jakes S, Hayashi J.J Immunol. 2000 May 15;164(10):5199-206.
- Applications
- Western Blot (Cell lysate)
- SH2B3 polyclonal antibody (Cat # PAB6669) (0.3 ug/mL) staining of MOLT 4 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 10019
- Protein Accession#:
- NP_005466.1
- Gene Name:
- SH2B3
- Gene Alias:
- CELIAC13,LNK
- Gene Description:
- SH2B adaptor protein 3
- Omim ID:
- 605093
- Gene Ontology:
- Hyperlink
- Gene Summary:
- T-cell activation requires stimulation of the T-cell receptor (TCR; see MIM 186880)-CD3 (see CD3Z; MIM 186780) complex, followed by recruitment of an array of intracellular signaling proteins (e.g., GRB2 (MIM 108355) and PLCG1 (MIM 172420)). Mediating the interaction between the extracellular receptors and intracellular signaling pathways are adaptor proteins such as LAT (MIM 602354), TRIM (MIM 604962), and LNK.[supplied by OMIM
- Other Designations:
- lymphocyte adaptor protein
- Gene Pathway