FITC标记的白细胞介素19抗体
产品名称： FITC标记的白细胞介素19抗体
英文名称： Anti-IL-19/FITC
产品编号： HZ-10087R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-IL-19/FITC Conjugated antibody
FITC标记的白细胞介素19抗体
| 英文名称 | Anti-IL-19/FITC |
| 中文名称 | FITC标记的白细胞介素19抗体 |
| 别 名 | Interleukin-19; IL 10C; IL 19; Interleukin 19; MDA1;ZMDA1; IL-19; Melanoma differentiation-associated protein-like protein; NG.1; IL19_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 20kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-19/NG.1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq]. Function: May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis. Subcellular Location: Secreted. Similarity: Belongs to the IL-10 family. Database links: Entrez Gene: 29949 Human Entrez Gene: 329244 Mouse Omim: 605687 Human SwissProt: Q9UHD0 Human SwissProt: Q8CJ70 Mouse Unigene: 661017 Human Unigene: 131480 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
由该基因编码的蛋白质是属于IL10细胞因子亚家族的细胞因子。这种细胞因子被发现在单核细胞中优先表达。它可以结合IL20受体复合物，导致信号转导和转录激活因子3（STAT3）的激活。据报道，一种类似的细胞因子在小鼠体内上调IL6和TNF-α的表达并诱导细胞凋亡，这表明该细胞因子在炎症反应中的作用。另外，已经描述了编码不同亚型的剪接转录变体。[由RefSeq提供]。