EBP2,EB病毒核抗原1结合蛋白2抗体

产品编号HZ-14495R
英文名称EBP2
中文名称EB病毒核抗原1结合蛋白2抗体
别 名EBNA1-binding protein 2; EBNA1 binding protein 2; ebna1bp2; EBP2; EBP2_HUMAN; NOBP; nuclear FGF3 binding protein; Nucleolar protein p40; P40; Probable rRNA processing protein EBP2; Probable rRNA-processing protein ebp2.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细菌及病毒
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat,
EBP2,EB病毒核抗原1结合蛋白2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量36kDa
细胞定位细胞核
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human EBP2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
EBP2,EB病毒核抗原1结合蛋白2抗体PubMedPubMed
产品介绍background:
The replication and stable maintenance of latent Epstein-Barr virus DNA episomes in human cells requires only one viral protein, Epstein-Barr nuclear antigen 1 (EBNA1). EBNA1 binding protein 2, also designated p40/EBP2, is a nuclear protein required for the processing of the 27S pre-rRNA. EBP2 is highly conserved across species and is ubiquitously expressed in human tissues, especially myelogenous leukemia K-562. EBP2 specifically interacts with EBNA1, supporting the long-term maintenance of Epstein-Barr virus plasmids in human cells. The EBNA1-EBP2 complex is important for the stable segregation of Epstein-Barr virus episomes during cell division.

Function:
Required for the processing of the 27S pre-rRNA

Subcellular Location:
Nucleus > nucleolus.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the EBP2 family.

Database links:
Entrez Gene: 10969 Human
Omim: 614443 Human
SwissProt: Q99848 Human
Unigene: 346868 Human

EBP2,EB病毒核抗原1结合蛋白2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.