Claudin 18 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
Claudin 18 抗体

Claudin 18 抗体

商家询价

产品名称： Claudin 18 抗体

英文名称： Claudin 18 Antibody

产品编号： XY 21126-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 CLAUDIN 18 抗体

Applications
In-house applications ELISA, WB, IP, IHC     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
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  • 21126-1-AP;human stomach tissueImmunohistochemistry of paraffin-embedded human stomach tissue slide using 21126-1-AP( CLDN18 Antibody) at dilution of 1:200 (under 10x lens).
  • 21126-1-AP;human stomach tissueImmunohistochemistry of paraffin-embedded human stomach tissue slide using 21126-1-AP( CLDN18 Antibody) at dilution of 1:200 (under 40x lens).
  • 21126-1-AP;mouse stomach tissueIP Result of anti-CLDN18 (IP:21126-1-AP, 3ug; Detection:21126-1-AP 1:500) with mouse stomach tissue lysate 4000ug.
  • 21126-1-AP;mouse kidney tissuemouse kidney tissue were subjected to SDS PAGE followed by western blot with 21126-1-AP(CLDN18 antibody) at dilution of 1:500
Positive WB detected in Mouse kidney tissue
Positive IP detected in Mouse stomach tissue
Positive IHC detected in Human stomach tissue, human ovary tumor tissue, human pancreas cancer tissue, human stomach cancer tissue
Recommended dilution WB : 1:200-1:2000
IP : 1:200-1:2000
IHC : 1:50-1:400
 CLAUDIN 18 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen Claudin 18 fusion protein ag15517 Full name Claudin 18
Calculated molecular
weight		 261aa,28 kDa Observed molecular 
weight		 28-29 kDa
GenBank accession 
number		 BC146668 Gene ID (NCBI) 51208
Gene symbol CLDN18 Synonyms Claudin 18, CLDN18, SFTA5, SFTPJ
Background CLAUDIN 18 抗体

Claudin 18 (CLDN18) belongs to the large claudin family of proteins, which are tetraspan transmembrane proteins of tight junctions (PMID: 11585919; 18036336). Claudins exhibit specific patterns of expression in different tissues (PMID: 15447685). CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific (PMID: 11585919; 21832145). Altered CLDN18 expression has been reported in various human malignancies, including gastric cancer, lung adenocarcinoma, and pancreatic neoplasm (PMID: 17459057; 22076167; 21832145). CLAUDIN 18 抗体

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