FITC标记的线粒体苹果酸脱氢酶2抗体
产品名称： FITC标记的线粒体苹果酸脱氢酶2抗体
英文名称： Anti-MDH2/FITC
产品编号： HZ-20126R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-MDH2/FITC Conjugated antibody
FITC标记的线粒体苹果酸脱氢酶2抗体
| 英文名称 | Anti-MDH2/FITC |
| 中文名称 | FITC标记的线粒体苹果酸脱氢酶2抗体 |
| 别 名 | M MDH; Malate dehydrogenase 2, NAD (mitochondrial); Malate dehydrogenase; Malate dehydrogenase, mitochondrial; MDH; mdh2; MDHM_HUMAN; MGC:3559; mitochondrial; Mitochondrial malate dehydrogenase 2, NAD; Mor 1; MOR1; OTTMUSP00000026139. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 新陈代谢 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 33kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MDH2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013] Subunit: Homodimer. Subcellular Location: Mitochondrion matrix. Post-translational modifications: Acetylation is enhanced by up to 67% after treatment either with trichostin A (TSA) or with nicotinamide (NAM) with the appearance of tri-and tetraacetylations. Glucose also increases acetylation by about 60%. Similarity: Belongs to the LDH/MDH superfamily. MDH type 1 family. Database links: Entrez Gene: 4191 Human Entrez Gene: 17448 Mouse Entrez Gene: 81829 Rat Omim: 154100 Human SwissProt: P40926 Human SwissProt: P08249 Mouse SwissProt: P04636 Rat Unigene: 520967 Human Unigene: 297096 Mouse Unigene: 1011 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
苹果酸脱氢酶利用柠檬酸循环中的NAD/NADH辅因子系统，催化苹果酸可逆氧化成草酰乙酸酯。该基因编码的蛋白定位于线粒体，在苹果酸-天冬氨酸穿梭中扮演关键角色，该穿梭在细胞质和线粒体之间的代谢协调中起作用。已发现该基因的几个编码不同同工型的转录体变体。[ RefSeq，SEP 2013提供]