HCV NS5A transactivated protein 8,丙肝病毒NS5A反转录蛋白8抗体

产品编号HZ-8158R
英文名称HCV NS5A transactivated protein 8
中文名称丙肝病毒NS5A反转录蛋白8抗体
别 名BTB (POZ) domain containing 1; BTB domain containing 1; BTB/POZ domain containing protein 1; BTBD 1; C15orf1; HCV NS5A transactivated protein 8; Hepatitis C virus NS5A transactivated protein 8; NS5ATP8; BTBD1_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 细胞周期蛋白 转录调节因子 细菌及病毒 细胞分化
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
HCV NS5A transactivated protein 8,丙肝病毒NS5A反转录蛋白8抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human BTBD1/HCV NS5A transactivated protein 8
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
HCV NS5A transactivated protein 8,丙肝病毒NS5A反转录蛋白8抗体PubMedPubMed
产品介绍background:
BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation.

Function:
Probable substrate-specific adapter of an E3ubiquitin-protein ligase complex which mediates the ubiquitinationand subsequent proteasomal degradation of target proteins.

Subunit:
Interacts with topoisomerase 1 and with TRIM5 isoformDelta. Interacts with CUL3.

Subcellular Location:
Cytoplasm, P-body. Note=Cytoplasmic bodies.

Tissue Specificity:
Ubiquitous; higher levels in heart andskeletal muscle.

Post-translational modifications:

Similarity:
Contains 1 BTB (POZ) domain.

HCV NS5A transactivated protein 8,丙肝病毒NS5A反转录蛋白8抗体Database links:
UniProtKB/Swiss-Prot: Q9H0C5.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.