BAIAP2L2,BAIAP2L2蛋白抗体

产品编号HZ-13684R
英文名称BAIAP2L2
中文名称BAIAP2L2蛋白抗体
别 名BAI1-associated protein 2-like 2; BAI1-associated protein 2-like protein 2; baiap2l2; BAIAP2L2 BAI1-associated protein 2-like 2; BC048937; BI2L2_HUMAN; Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2; FLJ22582; Pinkbar; Planar intestinal- and kidney-specific BAR domain protein; RP5-1039K5.3.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 神经生物学 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse,
BAIAP2L2,BAIAP2L2蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量59kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human BAIAP2L2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
BAIAP2L2,BAIAP2L2蛋白抗体PubMedPubMed
产品介绍background:
The Src homology 3 (SH3) domain is a highly conserved 60 amino acid protein domain that is organized into a beta-barrel fold consisting of five or six beta strands arranged as two tightly packed anti-parallel beta sheets. This domain is found in proteins that mediate assembly of specific protein complexes and interact with other proteins, specifically recognizing proline-rich regions. BAIAP2L2 (Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2) is a 529 amino acid protein containing an SH3 domain, suggesting that it may function as an adaptor protein. BAIAP2L2 also contains an IMD (IRSp53/MIM) domain, which enables the protein to bind to and bundle Actin filaments, as well as bind to membranes and interact with Rac GTPase. There are two named isoforms of BAIAP2L2 which are produced as a result of alternative splicing events.

Function:
May function as an adapter protein.

Subcellular Location:
Cell membrane; Peripheral membrane protein. Cell junction. Cytoplasmic vesicle membrane. Note=Localizes to RAB13-positive vesicles and to the plasma membrane at intercellular contacts.

Tissue Specificity:
Expressed in the epithelial layer of the intestine (at protein level).

Similarity:
Contains 1 IMD (IRSp53/MIM homology) domain.
Contains 1 SH3 domain.

BAIAP2L2,BAIAP2L2蛋白抗体Database links:
Entrez Gene: 80115 Human
SwissProt: Q6UXY1 Human
Unigene: 474822 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.