Phospho-Src-Y529 Rabbit pAb (AMR00866N)
产品名称: Phospho-Src-Y529 Rabbit pAb (AMR00866N)
英文名称: Phospho-Src-Y529 Rabbit pAb (AMR00866N)
产品编号: AMR00866N
产品价格: null
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: WB (Human lung cancer cell, Mus musculus, Homo sapiens, Rattus norvegicus) IHC (Mus musculus) IF (Mus musculus, Rattus n
分子量:Calculated MW: 59kDa/60kDa Observed MW: 60KDa 细胞定位:Cell membrane, Cytoplasm, Mitochondrion inner membrane, Nucleus, cytoskeleton 稀释方法:WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:100 - 1:200 总结:This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.