FITC标记的视网膜短链脱氢酶/还原酶家族7抗体
产品名称： FITC标记的视网膜短链脱氢酶/还原酶家族7抗体
英文名称： Anti-DHRS7/FITC
产品编号： HZ-8262R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-DHRS7/FITC Conjugated antibody
FITC标记的视网膜短链脱氢酶/还原酶家族7抗体
| 产品编号 | bs-8262R-FITC |
| 英文名称 | Anti-DHRS7/FITC |
| 中文名称 | FITC标记的视网膜短链脱氢酶/还原酶家族7抗体 |
| 别 名 | CGI 86; CGI86; Dehydrogenase/reductase SDR family member 7; DHRS7A; retDSR4; Retinal short chain dehydrogenase/reductase 4; RETSDR4; DHRS7_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 发育生物学 神经生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 35kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DHRS7 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: DHRS7 (dehydrogenase/reductase (SDR family) member 7), also known as SDR34C1, CGI-86 or retSDR4, is a 339 amino acid member of the SDR family. Like other members of the SDR family, DHRS7 contains a cofactor-binding Rossman-fold domain and is thought to catalyze the oxidation and reduction of a variety of substrates such as steroids and retinoids. DHRS7 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. Database links: UniProtKB/Swiss-Prot: Q9Y394.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
DHS7（脱氢酶/还原酶（SDR家族）成员7），也称为SDR34 C1，CGI -86/RESTRD4，是SDR家族的339氨基酸成员。与SDR家族的其他成员一样，DHS7包含辅因子结合罗斯曼折叠结构域，并被认为催化多种底物如甾体和维甲酸类化合物的氧化和还原。DHS7作为两个交替剪接的亚型存在，该亚型由位于人类14号染色体上的基因编码，所述基因包含700个以上的基因，并包含人类基因组的近3.5%。第14号染色体编码了早老素1（PSEN1）基因，这是与阿尔茨海默病（AD）发展相关的三个关键基因之一。SerpIA1基因也位于14号染色体上，当有缺陷时，会导致遗传障碍？抗胰蛋白酶缺乏症，表现为严重的肺部并发症和肝功能不全。