FITC标记的钾电压阀门通道混合器相关亚家族成员7抗体
产品名称： FITC标记的钾电压阀门通道混合器相关亚家族成员7抗体
英文名称： Anti-KCNA7/FITC
产品编号： HZ-3656R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-KCNA7/FITC Conjugated antibody
FITC标记的钾电压阀门通道混合器相关亚家族成员7抗体
| 英文名称 | Anti-KCNA7/FITC |
| 中文名称 | FITC标记的钾电压阀门通道混合器相关亚家族成员7抗体 |
| 别 名 | HAK 6; HAK6; KCNA 7; KV1.7; Potassium voltage gated channel shaker related subfamily member 7; Potassium voltage gated channel subfamily A member 7; Voltage dependent potassium channel Kv1.7; Voltage gated potassium channel KCNA7; Voltage gated potassium channel subunit Kv1.7. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 免疫学 神经生物学 通道蛋白 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Rabbit, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 50kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KCNA7 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. The gene is expressed preferentially in skeletal muscle, heart and kidney. It is a candidate gene for inherited cardiac disorders. [provided by RefSeq, Jul 2008] Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient (By similarity). Subunit: Heterotetramer of potassium channel proteins. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Highly expressed in skeletal muscle, heart and kidney. Similarity: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.7/KCNA7 sub-subfamily. Database links: Entrez Gene: 3743 Human Entrez Gene: 16495 Mouse Entrez Gene: 365241 Rat Omim: 176268 Human SwissProt: Q96RP8 Human SwissProt: Q17ST2 Mouse Unigene: 306973 Human Unigene: 12955 Mouse Unigene: 218566 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
钾通道是功能门控和结构观点的最复杂的电压门控离子通道。它们的多种功能包括调节神经递质释放、心率、胰岛素分泌、神经元兴奋性、上皮电解质转运、平滑肌收缩和细胞体积。在Drosophila已经鉴定出四个与序列相关的钾通道基因——振子、肖、SaB和Sal-，每个都显示有人类同源物（S）。该基因编码钾通道的成员，电压门控，振荡器相关子家族。该成员包含六个跨膜结构域，在第四段中具有振动器类型的重复。该基因在骨骼肌、心脏和肾脏中优先表达。它是遗传性心脏病的候选基因。[ RefSeq，JUL 2008 ]