CD147抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
CD147抗体

CD147抗体

商家询价

产品名称: CD147抗体

英文名称: CD147Antibody

产品编号: XY11989-1

产品价格: null

产品产地: 中国/美国

品牌商标: XYbscience

更新时间: 2023-08-17T09:55:27

使用范围: WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
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 CD147抗体

Applications
In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Published applications IHC, WB Publications 6 citations –view here
Species specificity Human; other species not tested.
Published Species Human, mouse
Images
Prev1NextView more validation data
  • 11989-1-AP;human liver tissuehuman liver tissue were subjected to SDS PAGE followed by western blot with 11989-1-AP(CD147 antibody) at dilution of 1:500
  • 11989-1-AP;human lung cancerImmunohistochemical of paraffin-embedded human lung cancer using 11989-1-AP(CD147 antibody) at dilution of 1:100 (under 10x lens)
  • 11989-1-AP;HEK-293 cellsIP Result of anti-CD147 (IP:11989-1-AP, 4ug; Detection:11989-1-AP 1:300) with HEK-293 cells lysate 2800ug.
Positive WB detected in Human liver tissue
Positive IP detected in HEK-293 cells
Positive IHC detected in Human lung cancer tissue, human breast cancer tissue, human gliomas tissue, human liver cancer tissue
Recommended dilution WB : 1:1000-1:10000
IP : 1:200-1:1000
IHC : 1:20-1:200
 CD147抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen CD147 fusion protein ag2619 Full name Basigin (Ok blood group)
Calculated molecular
weight
385aa,42 kDa Observed molecular 
weight
34 kDa+50 kDa
GenBank accession 
number
BC009040 Gene ID (NCBI) 682
Gene symbol BSG Synonyms 5F7, Basigin, basigin (Ok blood group), BSG, CD147, Collagenase stimulatory factor, EMMPRIN, HAb18G, M6, OK, OK blood group antigen, TCSF
Background CD147抗体

BSG, also named as 5F7, Basigin, EMMPRIN, TCSF and CD147, plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. It stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS).CD147 may target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. It seems to be a receptor for oligomannosidic glycans. CD147 is a receptor of CypA, inducing matrix metalloproteinase expression and mediating the degradation of the extracellular matrix, plays an important role in tumorigenesis and invasion in oral cancer. It has been considered as an objective and effective marker to predict invasion and prognosis in various cancers. CD147抗体

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