PLEKHM3,血小板白细胞C激酶底物同源结构域M3抗体

产品编号HZ-8064R
英文名称PLEKHM3
中文名称血小板白细胞C激酶底物同源结构域M3抗体
别 名DAPR; PH domain containing family M member 3; PH domain-containing family M member 3; PKHM3_HUMAN; Pleckstrin homology domain containing family M member 3; Pleckstrin homology domain-containing family M member 3; PLEKHM1L; Plekhm3.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 发育生物学 细胞周期蛋白 细胞分化
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit,
PLEKHM3,血小板白细胞C激酶底物同源结构域M3抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量87kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human PLEKHM3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PLEKHM3,血小板白细胞C激酶底物同源结构域M3抗体PubMedPubMed
产品介绍background:
PLEKHM3 (pleckstrin homology domain containing, family M, member 3), also known as DAPR or PLEKHM1L (pleckstrin homology domain containing, family M, member 1-like), is a 761 amino acid phosphoprotein that contains two pleckstrin homology (PH) domains and one phorbol-ester/DAG-type zinc finger. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PLEKHM3 exists as three alternatively spliced isoforms that participate in metal ion binding. The gene that encodes PLEKHM3 maps to human chromosome 2q33.3. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.

Similarity:
Contains 2 PH domains.
Contains 1 phorbol-ester/DAG-type zinc finger.

PLEKHM3,血小板白细胞C激酶底物同源结构域M3抗体Database links:
UniProtKB/Swiss-Prot: Q6ZWE6.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.