FITC标记的延伸因子G2抗体-抗体-抗体-生物在线
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FITC标记的延伸因子G2抗体

FITC标记的延伸因子G2抗体

商家询价

产品名称： FITC标记的延伸因子G2抗体

英文名称： Anti-GFM2/FITC

产品编号： HZ-13339R-FITC

产品价格： null

产品产地： 中国/上海

品牌商标： HZbscience

更新时间： 2023-08-17T10:24:20

使用范围： ICC=1:50-200 IF=1:50-200

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 Rabbit Anti-GFM2/FITC Conjugated antibody

FITC标记的延伸因子G2抗体

 

英文名称 Anti-GFM2/FITC
中文名称 FITC标记的延伸因子G2抗体
别    名 EF-G2mt; EFG2; EFG2mt; elongation factor G 2, mitochondrial; Elongation factor G2; G elongation factor mitochondrial 2; GFM2; hEFG2; mEFG 2; mEFG2; Mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; MRRF2; MST027; MSTP027; OTTHUMP00000222951; OTTHUMP00000222952; ribosome-releasing factor 2, mitochondrial; RRF2; RRF2mt.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 细胞生物  线粒体  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Sheep, 
产品应用 ICC=1:50-200 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 87kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GFM2
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
GFM2 is a mitochondrial translation elongation factor. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA.

Function:
Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. 

Subcellular Location:
Mitochondrial.

Tissue Specificity:
Widely expressed. 

Similarity:
Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily. 

Database links:
UniProtKB/Swiss-Prot: Q969S9.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications
   
   

一个伸长因子gfm2线粒体翻译。它的作用在调节线粒体功能的正常和在不同的疾病中线粒体功能障碍是一个众所周知的被浸出。翻译后eukaryotes蛋白包含两个系统，一个在细胞质和线粒体中。线粒体是至关重要的维持线粒体功能的翻译和在本系统的突变导致击穿在氧化呼吸链A和phosphorylation系统受损线粒体DNA维修）。