FITC标记的RAS癌基因家族蛋白RAB40B抗体
产品名称： FITC标记的RAS癌基因家族蛋白RAB40B抗体
英文名称： Anti-RAB40B/FITC
产品编号： HZ-8365R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-RAB40B/FITC Conjugated antibody
FITC标记的RAS癌基因家族蛋白RAB40B抗体
| 产品编号 | bs-8365R-FITC |
| 英文名称 | Anti-RAB40B/FITC |
| 中文名称 | FITC标记的RAS癌基因家族蛋白RAB40B抗体 |
| 别 名 | SEC4L; GTP binding protein homologous to Saccharomyces cerevisiae SEC4; RAB40B member RAS oncogene family; RAR; Rar protein; Ras related protein Rab 40B; RP23 293H17.2; SOCS box containing protein RAR; FLJ42385; RB40B_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 免疫学 信号转导 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 31kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RAB40B |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: RAB40B is similar to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. It may be a substrate recognition component of a SCF like ECS (Elongin Cullin SOCS box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Subcellular Location: Cell membrane; Lipid anchor; Cytoplasmic side. Similarity: Belongs to the small GTPase superfamily. Rab family. Contains 1 SOCS box domain. Database links: Entrez Gene: 10966 Human Entrez Gene: 217371 Mouse Entrez Gene: 303754 Rat SwissProt: Q12829 Human SwissProt: Q8VHP8 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
Rab40B类似于酵母蛋白，提示基因产物在调节分泌囊泡中的作用。它可能是SCF样ECS（细长Culin SOCS盒蛋白）E3泛素连接酶复合物的底物识别成分，介导泛素化和随后的蛋白酶体降解靶蛋白。