FITC标记的肺Kruppel样因子抗体
产品名称： FITC标记的肺Kruppel样因子抗体
英文名称： Anti-KLF2/FITC
产品编号： HZ-2772R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： Flow-Cyt=1:50-200 IF=1:50-200 not yet tested in other applications.
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Rabbit Anti-KLF2/FITC Conjugated antibody
FITC标记的肺Kruppel样因子抗体
| 英文名称 | Anti-KLF2/FITC |
| 中文名称 | FITC标记的肺Kruppel样因子抗体 |
| 别 名 | Kruppel like factor 2; Kruppel like factor; Kruppel like factor LKLF; Kruppel-like factor 2 (lung); Lung krueppel like factor; Lung Kruppel like zinc finger transcription factor; KLF 2; Klf2; KLF2_HUMAN; Krueppel-like factor 2; Lklf; Lung krueppel like factor; Lung krueppel-like factor; Lung Kruppel like zinc finger transcription factor. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 信号转导 转录调节因子 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | Flow-Cyt=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KLF2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1; MIM 601974) and the selectin CD62L (SELL; MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011] Function: Binds to the CACCC box in the beta-globin gene promoter and activates transcription . Subunit: Interacts with WWP1. Subcellular Location: Nucleus. Post-translational modifications: Ubiquitinated. Polyubiquitination involves WWP1 and leads to proteasomal degradation of this protein. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 3 C2H2-type zinc fingers. Database links: Entrez Gene: 10365 Human Entrez Gene: 16598 Mouse Entrez Gene: 306330 Rat Omim: 602016 Human SwissProt: Q9Y5W3 Human SwissProt: Q60843 Mouse SwissProt: Q9ET58 Rat Unigene: 107740 Human Unigene: 726356 Human Unigene: 26938 Mouse Unigene: 92653 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
KrpPEL样因子（KLFS）是一个广泛表达的锌指转录因子家族。KLF2通过促进脂质结合受体S1P1（S1PR1；MIM 601974）和选择素CD62L（Surviv:MIM 153240）的表达来调节T细胞的运输。（WeeRemik等人，2009 [ PubMed 19592277 ]的摘要）。