FITC标记的胆固醇24α7羟化酶抗体
产品名称: FITC标记的胆固醇24α7羟化酶抗体
英文名称: Anti-CYP39A1/FITC
产品编号: HZ-5050R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-CYP39A1/FITC Conjugated antibody
FITC标记的胆固醇24α7羟化酶抗体
英文名称 | Anti-CYP39A1/FITC |
中文名称 | FITC标记的胆固醇24α7羟化酶抗体 |
别 名 | 24 hydroxycholesterol 7 alpha hydroxylase; cytochrome P450 family 39, subfamily A polypeptide 1; cytochrome P450 subfamily XXXIX (oxysterol 7 alpha hydroxylase) polypeptide 1 ; hCYP39A1; Oxysterol 7 alpha hydroxylase; oxysterol 7alpha hydroxylase; CP39A_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 免疫学 信号转导 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Horse, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 54kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CYP39A1 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: The CYP39A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of steroids, cholesterol and other lipids. This endoplasmic reticulum protein is involved in the conversion of cholesterol to bile acids. Its substrates include the oxysterols 25-hydroxycholesterol, 27-hydroxycholesterol and 24-hydroxycholesterol. Function: Involved in the bile acid metabolism. Has a preference for 24-hydroxycholesterol, and converts it into a 7-alpha-hydroxylated product. Subcellular Location: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Tissue Specificity: Liver specific. Similarity: Belongs to the cytochrome P450 family. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
CYP39 A1基因编码细胞色素P450酶家族的一个成员。细胞色素P450蛋白是单加氧酶,它催化药物代谢和类固醇、胆固醇和其他脂质合成的许多反应。内质网蛋白参与胆固醇向胆汁酸的转化。其底物包括氧化甾醇25羟基胆固醇、27羟基胆固醇和24羟胆甾醇。