ABL1-Specific抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ABL1-Specific抗体

ABL1-Specific抗体

商家询价

产品名称： ABL1-Specific抗体

英文名称： ABL1-SpecificAntibody

产品编号： XY19772-1-

产品价格： null

产品产地： 中国/美国

品牌商标： 信裕生物

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 ABL1-SPECIFIC抗体

Applications
Tested Applications: ELISA
Specificity Reaction: Human, mouse, rat; Other species are not tested.Please decide the specificity by homology
Recommended dilution  
 ABL1-SPECIFIC抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.1% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: Peptide Full Name: C-abl oncogene 1, receptor tyrosine kinase
Caculated Molecular
Weight:		 123 kDa Observed Molecular 
Weight:		  
GenbankNo NM_005157 GeneID: 25
Symbol ABL1 Synonyms ABL1, Tyrosine protein kinase ABL1, p150, v abl, Proto oncogene c Abl
Background ABL1-SPECIFIC抗体

ABL1, also named as ABL, JTK7, c-ABL and p150, belongs to the protein kinase superfamily, Tyr protein kinase family and ABL subfamily. ABL1 regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. ABL1 localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. It regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. ABL1 catalyze the reaction: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. A chromosomal aberration involving ABL1 is a cause of chronic myeloid leukemia (CML) [MIM:608232]. Translocation t(9;22)(q34;q11) with BCR. The translocation produces a BCR-ABL found also in acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). The antibody is specific to ABL1. ABL1-SPECIFIC抗体

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