FGFR1OP2,FGFR1癌基因伴侣蛋白2抗体-抗体-抗体-生物在线
上海沪震实业有限公司
FGFR1OP2,FGFR1癌基因伴侣蛋白2抗体

FGFR1OP2,FGFR1癌基因伴侣蛋白2抗体

商家询价

产品名称: FGFR1OP2,FGFR1癌基因伴侣蛋白2抗体

英文名称: Anti-FGFR1OP2 antibody

产品编号: HZ-8346R

产品价格: null

产品产地: 中国/美国

品牌商标: HZbscience

更新时间: 2023-08-17T10:24:20

使用范围: WB,ELISA,IHC-P,IHC-F,IF

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FGFR1OP2,FGFR1癌基因伴侣蛋白2抗体

产品编号HZ-8346R
英文名称FGFR1OP2
中文名称FGFR1癌基因伴侣蛋白2抗体
别 名DKFZp564O1863; FGFR1 oncogene partner 2; HSPC123; HSPC123 like; FGOP2_HUMAN.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 信号转导 生长因子和激素 激酶和磷酸酶
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Horse, Rabbit,
FGFR1OP2,FGFR1癌基因伴侣蛋白2抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量29kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human FGFR1OP2
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
FGFR1OP2,FGFR1癌基因伴侣蛋白2抗体PubMedPubMed
产品介绍background:
FGFR1OP2 belongs to the SIKE family. The FGFR1OP2 (FGFR1 oncogene partner 2) gene was identified through its involvement in a fusion with the FGFR1 gene. FGFR1OP2 may be involved in the wound healing pathway. It is expressed in bone marrow, spleen and thymus. A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T cell or B cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.

Function:
May be involved in wound healing pathway (By similarity).

Subcellular Location:
Cytoplasm (By similarity).

FGFR1OP2,FGFR1癌基因伴侣蛋白2抗体Tissue Specificity:
Expressed in bone marrow, spleen and thymus.

DISEASE:
Note=A chromosomal aberration involving FGFR1OP2 may be a cause of stem cell myeloproliferative disorder (MPD). Insertion ins(12;8)(p11;p11p22) with FGFR1. MPD is characterized by myeloid hyperplasia, eosinophilia and T-cell or B-cell lymphoblastic lymphoma. In general it progresses to acute myeloid leukemia. The fusion protein FGFR1OP2-FGFR1 may exhibit constitutive kinase activity and be responsible for the transforming activity.

Similarity:
Belongs to the SIKE family.

Database links:
UniProtKB/Swiss-Prot: Q9NVK5.1

FGFR1OP2,FGFR1癌基因伴侣蛋白2抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.