CCDC51,卷曲螺旋结构域蛋白51抗体

产品编号HZ-6925R
英文名称CCDC51
中文名称卷曲螺旋结构域蛋白51抗体
别 名CCD51_HUMAN; CCDC51; Coiled-coil domain-containing protein 51; FLJ12436; RGD1311466; AI551049; 5730568A12Rik.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
CCDC51,卷曲螺旋结构域蛋白51抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量45kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CCDC51
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CCDC51,卷曲螺旋结构域蛋白51抗体PubMedPubMed
产品介绍background:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC51 (coiled-coil domain containing 51) is a 411 amino acid multi-pass membrane protein that exists as two alternatively spliced isoforms. The gene encoding CCDC51 maps to human chromosome 3, which is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.

Subcellular Location:
Membrane; Multi-pass membrane protein (Potential).

Database links:
UniProtKB/Swiss-Prot: Q96ER9.2
Entrez Gene: 79714 Human
Entrez Gene: 66658 Mouse
Entrez Gene: 316008 Rat
SwissProt: Q96ER9 Human
SwissProt: Q3URS9 Mouse
SwissProt: Q5PPN7 Rat
Unigene: 187657 Human

CCDC51,卷曲螺旋结构域蛋白51抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.