CD48,CD48抗体

产品编号HZ-2497R
英文名称CD48
中文名称CD48抗体
别 名SLAMF2; Antigen CD48; Antigen CD48; B cell membrane protein; B lymphocyte activation marker BLAST 1 [Precursor]; B lymphocyte activation marker BLAST 1; B-lymphocyte activation marker BLAST-1; BCM 1 surface antigen; BCM1; BCM1 surface antigen; BCM1 surface antigen; BLAST 1; BLAST; BLAST1; BLAST1; CD 48; CD48; CD48 antigen (B cell membrane protein); CD48 antigen; CD48 molecule; CD48 protein; CD48_HUMAN; hCD48; Leucocyte antigen MEM 102; Leukocyte antigen MEM-102; mCD48; MEM 102; MEM102; SLAMF 2; TCT.1; TCT.1.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 信号转导 细胞表面分子 细胞类型标志物
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat, Pig, Cow,
CD48,CD48抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量22kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CD48
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
CD48,CD48抗体PubMedPubMed
产品介绍background:
CD48 is a glycosyl phophatidyl inositol (GPI) anchored cell surface protein also known as Blast1, HuLy m3, BCM1 (in mouse), and OX45 (in rat). CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibrolasts, epithelium and endothelium. CD48 is one of the markers for detecting the defects of GPI anchoring structure on patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2. The CD48 antigen is closely related to the activation antigen, Blast 1.

Function:
Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.

Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Gene ID:
962

CD48,CD48抗体Database links:
Entrez Gene: 962 Human
Omim: 109530 Human
SwissProt: P09326 Human
Unigene: 243564 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.