FITC标记的RAB3A相关样蛋白1抗体
产品名称： FITC标记的RAB3A相关样蛋白1抗体
英文名称： Anti-RAB3IL1/FITC
产品编号： HZ-19716R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-RAB3IL1/FITC Conjugated antibody
FITC标记的RAB3A相关样蛋白1抗体
| 英文名称 | Anti-RAB3IL1/FITC |
| 中文名称 | FITC标记的RAB3A相关样蛋白1抗体 |
| 别 名 | GRAB; Guanine nucleotide exchange factor for Rab 3A; guanine nucleotide exchange factor for Rab3A; Rab3A interacting like protein 1; RAB3A interacting protein (rabin3) like 1; Rabin3 like 1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 神经生物学 信号转导 G蛋白偶联受体 G蛋白信号 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 43kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RAB3IL1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a guanine nucleotide exchange factor for the ras-related protein Rab3A. The encoded protein binds Rab3a and the inositol hexakisphosphate kinase InsP6K1. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Nov 2012] Function: Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activate RAB8A and RAB8B. Subunit: Interacts with RAB3A and IHPK1 through the coiled-coil domain. This interaction is competitive. IHPK1 kinase activity is not required for this interaction (By similarity). Similarity: Belongs to the SEC2 family. Database links: Entrez Gene: 5866 Human Entrez Gene: 74760 Mouse Entrez Gene: 171452 Rat SwissProt: Q8TBN0 Human SwissProt: Q8VDV3 Mouse SwissProt: Q99NH3 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码一个小的GTP结合蛋白，属于Ras超家族中最大的家族。这些蛋白质作为膜运输的调节器起作用。它们在非活性的GDP结合态和活化的GTP结合态之间循环，后者受GTP水解活化蛋白（GAP）控制。该家族成员可由GAP蛋白RN TE激活，并定位于高尔基复合体。[ RefSeq，2010年5月提供]