FITC标记的锌指蛋白445抗体
产品名称： FITC标记的锌指蛋白445抗体
英文名称： Anti-Zinc finger protein 445/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Zinc finger protein 445/FITC Conjugated antibody
FITC标记的锌指蛋白445抗体
| 英文名称 | Anti-Zinc finger protein 445/FITC |
| 中文名称 | FITC标记的锌指蛋白445抗体 |
| 别 名 | MGC126535; OTTHUMP00000164036; Zinc finger protein 168; Zinc finger protein 445; Zinc finger protein with KRAB and SCAN domains 15; ZKSCAN15; ZN445_HUMAN; ZNF168; ZNF445. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 转录调节因子 锌指蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 119kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Zinc finger protein 445 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: ZNF445 is highly expressed in adult skeletal muscle and testis, while expressed at lower levels in small intestine, pancreas, colon, thymus, uterus and peripheral blood leukocytes. Overexpression of ZNF445 results in the activation of c-Jun and serum response element, suggesting a potential role in the MAPK signaling pathway. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 14 C2H2-type zinc fingers. Contains 1 KRAB domain. Contains 1 SCAN box domain. Database links: Entrez Gene: 353274 Human Entrez Gene: 235682 Mouse SwissProt: P59923 Human SwissProt: Q8R2V3 Mouse Unigene: 250481 Human Unigene: 326477 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
ZNF445在骨骼肌和睾丸中高表达，而在小肠、胰腺、结肠、胸腺、子宫和外周血白细胞中低表达。ZNF445的过表达导致c-Jun和血清应答元件的激活，提示MAPK信号通路可能起作用。