FITC标记的谷胱甘肽硫转移酶C段结构域抗体
产品名称： FITC标记的谷胱甘肽硫转移酶C段结构域抗体
英文名称： Anti-GSTCD/FITC
产品编号： HZ-8581R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-GSTCD/FITC Conjugated antibody
FITC标记的谷胱甘肽硫转移酶C段结构域抗体
| 产品编号 | bs-8581R-FITC |
| 英文名称 | Anti-GSTCD/FITC |
| 中文名称 | FITC标记的谷胱甘肽硫转移酶C段结构域抗体 |
| 别 名 | FLJ13273; Glutathione S transferase, C terminal domain containing; MGC74393; RGD1311822; GSTCD_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 71kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GSTCD |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Glutathione (GSH) is a tripeptide antioxidant that reduces disulfide bonds between cytoplasmic proteins. The constitutive enzyme glutathione reductase transforms glutathione into its reduced state, which ultimately can provide a measure of cellular toxicity. GSTCD (glutathione S-transferase, C-terminal domain containing) is a 633 amino acid protein belonging to the GSTCD family and contains one GST C-terminal domain. The gene encoding GSTCD maps to human chromosome 4, which represents approximately 6% of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Similarity: Belongs to the GSTCD family. Contains 1 GST C-terminal domain. Database links: UniProtKB/Swiss-Prot: Q8NEC7.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
谷胱甘肽（GSH）是一种三肽抗氧剂，能减少细胞质蛋白之间的二硫键。组成型酶谷胱甘肽还原酶将谷胱甘肽转化为其还原状态，最终可提供细胞毒性的测量。GSTCD（谷胱甘肽S-转移酶，C-末端结构域）是属于GSTCD家族的633个氨基酸，含有一个GST C-末端结构域。编码GSTCD的基因映射到人类4号染色体，其代表人类基因组的6%，并包含近900个基因。值得注意的是，亨廷顿氏症基因，发现编码的谷氨酰胺通道在亨廷顿氏病的情况下，是在4号染色体上。FGFR-3也编码在4号染色体上，并与致死性侏儒症、软骨发育不全、Munkes综合征和膀胱癌有关。第4号染色体也与Ellis van Creveld综合征、甲基丙二酸血症和多囊肾病有关。