FITC标记的FER1L5蛋白抗体
产品名称： FITC标记的FER1L5蛋白抗体
英文名称： Anti-FER1L5/FITC
产品编号： HZ-16072R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FER1L5/FITC Conjugated antibody
FITC标记的FER1L5蛋白抗体
| 英文名称 | Anti-FER1L5/FITC |
| 中文名称 | FITC标记的FER1L5蛋白抗体 |
| 别 名 | FR1L5_HUMAN; Fer1 like protein 5. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 发育生物学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 242kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FER1L5 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
| 产品介绍 | background: The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr鰉 syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes. Function: FER1L5 belongs to the ferlin family. There are three isoforms generated by alternative splicing. Subunit: Interacts (via second C2 domain) with EHD1 and EHD2 (By similarity). Subcellular Location: Cell Membrane; single pass membrane protein Similarity: Belongs to the ferlin family. Contains 6 C2 domains. Database links: Entrez Gene: 90342 Human SwissProt: A0AVI2 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
人类第二大染色体2由2.37亿个编码1400多个基因的碱基组成，约占人类基因组的8%。许多遗传疾病与2号染色体上的基因有关。丑角鳞癣，一种罕见的病态皮肤畸形，与ABCA12基因突变有关。脂类代谢紊乱是与ABCG5和ABCG8相关的。ALSTR综合征是一种极为罕见的隐性遗传性疾病，其原因在于ALMS1基因的突变。有趣的是，染色体2包含看起来是残留的第二着丝粒和残留端粒，这证实了人类染色体2是今天在猿类中以现代形式出现的两个祖先染色体的古老融合的结果。