人炎症反应和自身免疫miRNA PCR芯片用于研究调节促炎和抗炎基因的表达的84个 miRNA的表达将。这个芯片为研究者提供了一个方便快速的方法来分析炎症和自身免疫性疾病最有可能相关的miRNA。根据生物信息学算法和数据库预测的调节已知与炎症相关的基因来进行挑选miRNA。

这个芯片的分析结果可以作为正常和病理炎症研究的分子标记。结果也可助于深入了解miRNA调节炎症基因表达的分子机制。

每张芯片含一个对照组使得分析数据时可以用相对定量ΔΔCT方法评估逆转录效率,基因组DNA污染,和PCR效率。利用这张芯片，通过实时定量PCR，可以简易且可靠地分析预测调节炎症和自身免疫反应基因的miRNA的表达。

miScript miRNA PCR芯片仅用于分子生物学应用。本产品不用于疾病的诊断、预防和治疗。

提供96孔板——384 -(4 x 96)板,和100孔板

let-7a-5p, let-7b-5p, let-7c, let-7d-5p, let-7e-5p, let-7f-5p, let-7g-5p, let-7i-5p, miR-98: ACVR2A, CCL7, CCR7, FASLG, GDF6, IL10, IL13, LY75, OSMR, POU2F2, TGFBR1.
miR-101-3p: ACVR2B, ERBB2IP, FOS, GFRA1, PROK2, PTGS2, SOCS2, SPRED1, TGFBR1.
miR-17-5p, miR-20a-5p, miR-20b-5p, miR-519d, miR-93-5p: BMPR2, CCL1, F3, ITCH, NR4A2, OSM, STAT3, TGFBR2, TNFRSF21, ZFP91.
miR-125a-5p, miR-125b-5p: BCL2, IL16, IL6R, IRF4, LIFR, M6PR, RFXANK, TNFSF4.
miR-128: ACVR2A, BMPR2, CSF1, F3, GREM1, HDAC5, IRF4, ITCH, KITLG, MAPK14, TGFBR1.
miR-130a-3p, miR-130b-3p, miR-301a-3p, miR-301b, miR-454-3p: ACVR1, BMP3, BMPR2, CAST, CCL1, CHST1, EDA, ERBB2IP, INHBB, LY75, TGFBR1, TGFBR2, TNFRSF1B.
miR-1324: ACVR2B, BCL2, BMPR2, CHST1, EDA, KITLG, NR3C1, PAX5.
miR-144-3p: ACVR2B, BCL6, CXCL12, EDA, FN1, KITLG, LIFR, TNFSF11, TTN.
miR-145-5p: ACVR2A, BMP3, GFRA1, NR4A2, SRGAP1, TGFBR2, TNFRSF11B.
miR-15a-5p, miR-15b-5p, miR-16-5p, miR-195-5p, miR-424-5p, miR-497-5p: ACVR2A, ACVR2B, CD28, CYP26B1, EDA, GHR, IRAK2, SPRED1, VEGFA.
miR-181a-5p, miR-181b-5p, miR-181c-5p, miR-181d: ACVR2A, ACVR2B, BMP3, IL1A, KITLG, LIF, TGFBR1, TNFRSF11B.
miR-186-5p: ACVR2B, BMP3, BMPR2, CXCL13, EDA, LEPR, PDGFA, VEGFA, YY1.
miR-19a-3p, miR-19b-3p: BMP3, BMPR2, CAST, CHST1, CNTFR, CXCL12, F3, LY75, MAPK14.
miR-202-3p: ACVR2A, ACVR2B, GDF6, GHR, IL10, LY75, POU2F2, TGFBR1.
miR-21-5p, miR-590-5p: BMPR2, CCL1, FASLG, IL12A, LIFR, OLR1.
miR-211-5p: BCL2, BMPR1A, M6PR, NR3C1, NR4A2, TGFBR2, ZFP91.
miR-23a-3p, miR-23b-3p: ATRN, CCL7, CXCL12, IL12B, IL6R, KITLG, M6PR, PROK2, TGFBR2, TPST1.
miR-29a-3p, miR-29b-3p, miR-29c-3p: CD276, HDAC4, IL1RAP, LIF, PTX3, TNFRSF1A, VEGFA.
miR-300, miR-381: ACVR2B, ATRN, BMPR2, F3, GFRA1, IL15RA, ITCH, NR3C1, YY1.
miR-302a-3p, miR-302b-3p, miR-302c-3p, miR-372, miR-373-3p, miR-520d-3p, miR-520e: BCL6, BMPR2, CXCL12, CXCL14, CYP26B1, HDAC4, LEFTY1, LEFTY2, NR4A2, TGFBR2.
miR-30a-5p, miR-30b-5p, miR-30c-5p, miR-30d-5p, miR-30e-5p: ACVR1, ATRN, IL1A, LEPR, LIFR, NR4A2.
miR-340-5p: CAST, CYP26B1, IL12A, ITCH, LIFR, NFKB1, NR3C1.
miR-34a-5p, miR-34c-5p, miR-449a, miR-449b-5p: ACVR2B, ASB1, BCL2, BMP3, CSF1R, GREM2, IL6R, KITLG, LDHA, NR4A2.
miR-374a-5p: ACVR2B, BMP2, CCL2, CEBPB, CYP26B1, IL10.
miR-410: ACVR2B, CSF2, ITCH, NAMPT, NR3C1, PTX3, STAT3, VEGFA, YY1.
miR-511: CYP26B1, GFRA1, NR4A2, SOCS2, TGFB3, YY1.
miR-513b: ACVR2A, CXCL5, FIGF, HDAC4, LIFR, PTGS2, TGFBR1, TNFSF4.
miR-519c-3p: ACVR1, BMPR2, CCL1, CXCL12, ERBB2IP, TGFBR2, TNFRSF21.
miR-524-5p: ACVR2B, ERBB2IP, IL1A, NR4A2, TGFB3, TNFSF11, YY1, ZFP91.
miR-543: ACVR2A, ACVR2B, CYP26B1, FGF12, FOS, GDF6, IL10, IL1A.
miR-545-3p: ACVR2B, BMPR2, CYP26B1, IL1A, PDGFB, TGFBR1.
miR-548e: ACVR2B, IL12B, IL1R1, INHBB, SPRED1, TGFBR1, VEGFA.
miR-548c-3p: BMPR2, F11R, GHR, GREM2, ITCH, LEPR, NAMPT, NFE2L1, NR3C1, PREX1, S1PR3, TGFBR2.
miR-548d-3p: ACVR2A, ACVR2B, BMPR1A, GDF6, HDAC4, M6PR, NAMPT, VEGFA.
miR-607: ACVR2B, BCL2, BMP3, BMPR2, CD28, CXCL14, IL12A, NAMPT, ZFP91.
miR-655: BCL6.
miR-656: ACVR1B, BMP3, CYP26B1, F3, IFNG, NR4A2, TNFSF4.
miR-875-3p: CAST, CD53, EDA, ITCH, NFAM1, NR4A2, STAT3.
miR-9-5p: BCL6, ERBB2IP, FGF12, HDAC5, INHBB, KITLG, LEP, TGFBR2, TNFRSF21