ENTPD7,CD39样蛋白2/ENTPD6抗体

产品编号HZ-14603R
英文名称ENTPD7
中文名称CD39样蛋白2/ENTPD6抗体
别 名DKFZp667O124; Ectonucleoside triphosphate diphosphohydrolase 7; ENTPD 7; ENTPD7; ENTP7_HUMAN; LALP 1; LALP1; Lysosomal apyrase like protein 1; NTPDase 7; NTPDase7.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep,
ENTPD7,CD39样蛋白2/ENTPD6抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量69kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ENTPD7
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ENTPD7,CD39样蛋白2/ENTPD6抗体PubMedPubMed
产品介绍background:
LALP1 is a 604 amino acid multi-pass membrane protein that belongs to the GDA1/CD39 NTPase family. Preferentially hydrolyzing nucleoside 5’-triphosphates, LALP1 and has an order of activity with respect to possible substrates, which is UTP > GTP > CTP. The gene that encodes LALP1 consists of approximately 51,740 bases and maps to human chromosome 10q24.2. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Function:
The ENTPD7 belongs to the GDA1/CD39 NTPase family and the gene resides on chromosome 10q23-q24 and contains 12 exons and 11 introns covering a genomic region of approximately 46 kilobase pairs. The subcellular localization and enzymatic activity of ENTPD7 indicated that ENTPD7 is indeed an endo-apyrase with substrate preference for nucleoside triphosphates UTP, GTP, and CTP.

Subcellular Location:
Cytoplasmic intracellular multi-pass membrane protein. Localizes to vesicular compartments.

Similarity:
Belongs to the GDA1/CD39 NTPase family.

Gene ID:
57089

ENTPD7,CD39样蛋白2/ENTPD6抗体Database links:
Entrez Gene: 57089 Human
Entrez Gene: 93685 Mouse
Entrez Gene: 309390 Rat
SwissProt: Q9NQZ7 Human
SwissProt: Q3TCT4 Mouse
Unigene: 716513 Human
Unigene: 296789 Mouse
Unigene: 169265 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.