FITC标记的卵母细胞TRO抗体
产品名称: FITC标记的卵母细胞TRO抗体
英文名称: Anti-Magphinin/FITC
产品编号: HZ-20312R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Magphinin/FITC Conjugated antibody
FITC标记的卵母细胞TRO抗体
英文名称 | Anti-Magphinin/FITC |
中文名称 | FITC标记的卵母细胞TRO抗体 |
别 名 | KIAA1114; MAGE d3; TROP_HUMAN; MAGE D3 antigen; MAGE superfamily protein; MAGED3; Magphinin; Melanoma Antigen Family D, 3; OTTHUMP00000180629; OTTHUMP00000180636; TRO. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 发育生物学 细胞粘附分子 肿瘤细胞生物标志物 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 144kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 2mg/1ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Magphinin |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes a membrane protein that mediates apical cell adhesion between trophoblastic cells and luminal epithelial cells of the endometrium and is implicated in the initial attachment during the process of embryo implantation. This gene is related to the MAGED gene family by sequence similarity and chromosome location. Multiple alternatively spliced transcript variants have been found for this gene; however, the full-length nature of some variants has not been defined. Trophinin is directly responsible for homophilic cell adhesion, and could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Function: Could be involved with bystin and tastin in a cell adhesion molecule complex that mediates an initial attachment of the blastocyst to uterine epithelial cells at the time of the embryo implantation. Directly responsible for homophilic cell adhesion. Subunit: Directly binds bystin, and indirectly tastin. Tissue Specificity: Strong expression at implantation sites. Found in the placenta from the sixth week of pregnancy. Was localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the level decreased and then disappeared from placental villi. Also found in macrophages. Similarity: Contains 1 MAGE domain. Database links: Entrez Gene: 56191 Human Entrez Gene: 7216 Human Omim: 300132 Human SwissProt: Q12816 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码膜蛋白,介导滋养层细胞和子宫内膜腔上皮细胞之间的顶端细胞粘附,并参与胚胎植入过程中的初始附着。该基因通过序列相似性和染色体定位与MAGED基因家族有关。已经发现该基因的多个选择性剪接的转录体变体,然而,一些变体的全长性质尚未确定。Trophinin直接负责同种细胞粘附,并且可能与细胞粘附分子复合物中的bystin和tastin有关,细胞粘附分子复合物介导胚胎植入时囊胚与子宫上皮细胞的初始粘附。