FITC标记的转录因子同源蛋白Nkx2.6抗体
产品名称： FITC标记的转录因子同源蛋白Nkx2.6抗体
英文名称： Anti-Nkx2.6/FITC
产品编号： HZ-19275R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Nkx2.6/FITC Conjugated antibody
FITC标记的转录因子同源蛋白Nkx2.6抗体
| 英文名称 | Anti-Nkx2.6/FITC |
| 中文名称 | FITC标记的转录因子同源蛋白Nkx2.6抗体 |
| 别 名 | CSX2; Homeobox protein NK-2 homolog F; homeobox protein NK2 homolog F; Homeobox protein Nkx-2.6; Homeobox protein Nkx2.6; NK2 homeobox 6; NK2 transcription factor related, locus 6 (Drosophila); NKX2-6; NKX26_HUMAN; NKX2F; NKX4 2; Tinman paralog. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 心血管 细胞生物 发育生物学 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Nkx2.6 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.[provided by RefSeq, Aug 2011] Function: In conjunction with NKX2-5, may play a role in both pharyngeal and cardiac embryonic development. Subcellular Location: Nucleus DISEASE: [MIM:217095]: A group of congenital heart defects involving the outflow tracts. Examples include truncus arteriosus communis, double-outlet right ventricle and transposition of great arteries. Truncus arteriosus communis is characterized by a single outflow tract instead of a separate aorta and pulmonary artery. In transposition of the great arteries, the aorta arises from the right ventricle and the pulmonary artery from the left ventricle. In double outlet of the right ventricle, both the pulmonary artery and aorta arise from the right ventricle. Similarity: Belongs to the NK-2 homeobox family. Contains 1 homeobox DNA-binding domain. Database links:
Entrez Gene: 137814 Human Entrez Gene: 18092 Mouse Omim: 611770 Human SwissProt: A6NCS4 Human SwissProt: P43688 Mouse Unigene: 532654 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码属于NK-2同源盒家族的同源盒蛋白。这种蛋白是一个脊椎动物的同源基因的果蝇同源盒蛋白称为'银'，这已被证明为心如背血管的发展是必不可少的。结合相关基因NKX2-5，该基因可能在咽部和心脏胚胎发育中起作用。该基因的突变与持续性动脉干有关。[ RefSeq，Aug 2011 ]