FITC标记的组蛋白H1.4样蛋白抗体
产品名称: FITC标记的组蛋白H1.4样蛋白抗体
英文名称: Anti-Histone H1.4/FITC
产品编号: HZ-10334R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-Histone H1.4/FITC Conjugated antibody
FITC标记的组蛋白H1.4样蛋白抗体
英文名称 | Anti-Histone H1.4/FITC |
中文名称 | FITC标记的组蛋白H1.4样蛋白抗体 |
别 名 | HIST1H1E; H1F4; Histone H1.4; Histone H1b; H14_HUMAN; Histone H1s-4; H1 histone family member 4; H1E; Hist1h1e; Histone 1 H1e; Histone cluster 1 H1e; Histone H1; MGC116819. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 信号转导 干细胞 细胞凋亡 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Dog, Rabbit, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Histone H1.4 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: Histone H1b are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Function: Histones H1 are necessary for the condensation of nucleosome chains into higher order structures. Subcellular Location: Nucleus. Chromosome. Post-translational modifications: Acetylated at Lys-26. Deacetylated at Lys-26 by SIRT1. Similarity: Belongs to the histone H1/H5 family. Contains 1 H15 (linker histone H1/H5 globular) domain. Database links: Entrez Gene: 3008 Human Entrez Gene: 50709 Mouse Omim: 142220 Human SwissProt: P10412 Human SwissProt: P43274 Mouse Unigene: 248133 Human Unigene: 170587 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
组蛋白H1B是真核生物中染色体纤维的核小体结构的基本核蛋白。核小体由包裹在组蛋白八聚体周围的约146bp的DNA组成,组蛋白八聚体由四个核心组蛋白(H2A、H2B、H3和H4)中的每个组蛋白对组成。染色质纤维通过连接组蛋白H1与核小体之间的DNA相互作用进一步致密,从而形成高阶染色质结构。该基因是无内含子的,编码组蛋白H1家族的成员。该基因的转录缺少波利亚尾,而是包含回文终止元件。该基因在6号染色体上的大组蛋白基因簇中发现。