FITC标记的转化生长因子β诱导蛋白3抗体（半胱氨酸和丝氨酸富含核蛋白1）
产品名称： FITC标记的转化生长因子β诱导蛋白3抗体（半胱氨酸和丝氨酸富含核蛋白1）
英文名称： Anti-AXUD1/FITC
产品编号： HZ-7696R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： Flow-Cyt=1:50-200 IF=1:50-200
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Rabbit Anti-AXUD1/FITC Conjugated antibody
FITC标记的转化生长因子β诱导蛋白3抗体（半胱氨酸和丝氨酸富含核蛋白1）
| 英文名称 | Anti-AXUD1/FITC |
| 中文名称 | FITC标记的转化生长因子β诱导蛋白3抗体（半胱氨酸和丝氨酸富含核蛋白1） |
| 别 名 | Axin 1 Up-regulated; Axin-1 up-regulated gene 1 protein; CSRN1_HUMAN; CSRNP-1; CSRNP1; Cysteine/serine-rich nuclear protein 1; DKFZp566F164; FAM130B; Protein URAX1; TAIP 3; TAIP-3; TGF beta induced apoptosis protein 3; TGF-beta-induced apoptosis protein 3; URAX1. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 细胞周期蛋白 转录调节因子 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | Flow-Cyt=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 64kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human AXUD1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. [provided by RefSeq, Jul 2008]. Function: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. May have a tumor-suppressor function. May play a role in apoptosis. Subcellular Location: Nucleus Tissue Specificity: Ubiquitous. Most abundantly expressed in lung, placenta, skeletal muscle, pancreas and leukocyte. Frequently down-regulated in lung, kidney, liver and colon cancers compared with their corresponding normal tissues. Similarity: Belongs to the AXUD1 family. Database links: UniProtKB/Swiss-Prot: Q96S65.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码一种定位于细胞核的蛋白质，并响应于Axin水平的升高而诱导该基因的表达。Wnt信号通路是由Axin负调控的，在早期发育中的轴形成中是重要的，并且该信号通路的受损调节经常参与肿瘤。与相应的正常组织中的表达水平相比，该基因在肿瘤中的表达水平降低表明该基因产物具有肿瘤抑制功能。[ RefSeq，JUL 2008 ]提供。