FITC标记的细胞色素C氧化酶蛋白6A1抗体
产品名称： FITC标记的细胞色素C氧化酶蛋白6A1抗体
英文名称： Anti-COX6A1/FITC
产品编号： HZ-14007R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-COX6A1/FITC Conjugated antibody
FITC标记的细胞色素C氧化酶蛋白6A1抗体
| 英文名称 | Anti-COX6A1/FITC |
| 中文名称 | FITC标记的细胞色素C氧化酶蛋白6A1抗体 |
| 别 名 | COX VIa L; COX VIa-L; COX6A; COX6A1; COX6AL; CX6A1_HUMAN; Cytochrome c oxidase polypeptide VIa liver; Cytochrome c oxidase polypeptide VIa-liver; Cytochrome c oxidase subunit 6A1; Cytochrome c oxidase subunit 6A1 mitochondrial; Cytochrome C oxidase subunit VIa homolog; Cytochrome c oxidase subunit VIA liver; Cytochrome c oxidase subunit VIa polypeptide 1; Cytochrome c oxidase subunit VIA-liver; MGC104500; mitochondrial. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 新陈代谢 线粒体 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 10kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human COX6A1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq, Jul 2008] Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Subcellular Location: Mitochondrion inner membrane. Similarity: Belongs to the cytochrome c oxidase subunit 6A family. Database links: Entrez Gene: 1337 Human Omim: 602072 Human SwissProt: P12074 Human Unigene: 369624 Human Unigene: 497118 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
细胞色素C氧化酶（COX）是线粒体呼吸链的末端酶，催化从细胞色素C还原为氧的电子传递。它是由线粒体基因编码的3个催化亚基和由核基因编码的多个结构亚基组成的杂合复合体。线粒体编码亚基在电子传递中起作用，而核编码亚基在复合物的调节和组装中起作用。该核基因通过亚基编码多肽1（肝脏亚型），在所有非肌肉组织中发现多肽1。亚基的多肽2（心脏/肌肉亚型）由不同的基因编码，仅存在于横纹肌中。这两个多肽共有66%个氨基酸序列同源性。据报道，在染色体1, 6、7q21、7q31-32和12上可能有几个假基因。然而，在染色体1P31.1上只有一个假基因（COX6A1P）被记录下来。[ RefSeq，JUL 2008 ]