DHRS13,短链脱氢还原酶13抗体

产品编号HZ-8261R
英文名称DHRS13
中文名称短链脱氢还原酶13抗体
别 名Dehydrogenase/reductase (SDR family) member 13; Dehydrogenase/reductase SDR family member 13; DHRS 13; MGC23280; OTTHUMP00000163522; SDR7C5; Short chain dehydrogenase/reductase family 7C member 5; DHR13_HUMAN.
说 明 书0.1ml 0.2ml
研究领域细胞生物 免疫学 发育生物学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Cow, Horse, Sheep,
DHRS13,短链脱氢还原酶13抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量38kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human DHRS13
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
DHRS13,短链脱氢还原酶13抗体PubMedPubMed
产品介绍background:
DHRS13 (dehydrogenase/reductase SDR family member 13), also known as UNQ419/PRO853, is a 377 amino acid secreted protein belonging to the short-chain dehydrogenases/reductases (SDR) family. DHRS13 is presumed to function as an oxidoreductase and is phosphorylated, potentially by ATM or ATR, upon DNA damage. DHRS13 exists as two isoforms produced by alternative splicing events. The gene encoding DHRS13 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are associated with chromosome 17.

Function:
Putative oxidoreductase (Potential).

Subcellular Location:
Secreted (Potential).

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR (By similarity).

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Database links:
UniProtKB/Swiss-Prot: Q6UX07.1

DHRS13,短链脱氢还原酶13抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.