Adrenodoxin,肾上腺皮质线粒体铁氧还蛋白抗体

产品编号HZ-11426R
英文名称Adrenodoxin
中文名称肾上腺皮质线粒体铁氧还蛋白抗体
别 名Adrenal ferredoxin; Adrenodoxin; Adrenodoxin, mitochondrial; ADX; ADX_HUMAN; FDX; fdx1; Ferredoxin 1; Ferredoxin-1; Hepatoredoxin; LOH11CR1D; Mitochondrial adrenodoxin; mitochondrial.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 神经生物学 信号转导 生长因子和激素 线粒体
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Sheep,
Adrenodoxin,肾上腺皮质线粒体铁氧还蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量13.5kDa
细胞定位细胞浆 线粒体
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Adrenodoxin/FDX (51-150aa)
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Adrenodoxin,肾上腺皮质线粒体铁氧还蛋白抗体PubMedPubMed
产品介绍background:
This gene encodes a small iron-sulfur protein that transfers electrons from NADPH through ferredoxin reductase to mitochondrial cytochrome P450, involved in steroid, vitamin D, and bile acid metabolism. Pseudogenes of this functional gene are found on chromosomes 20 and 21. [provided by RefSeq, Aug 2011]

Function:
Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).

Similarity:
Belongs to the adrenodoxin/putidaredoxin family.
Contains 1 2Fe-2S ferredoxin-type domain.

Database links:
Entrez Gene: 2230 Human
Entrez Gene: 14148 Mouse
Entrez Gene: 29189 Rat
Omim: 103260 Human
SwissProt: P10109 Human
SwissProt: P46656 Mouse
SwissProt: P24483 Rat
Unigene: 744 Human
Unigene: 1061 Mouse
Unigene: 440190 Mouse
Unigene: 6946 Rat

Adrenodoxin,肾上腺皮质线粒体铁氧还蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.