EHD1蛋白抗体

产品编号HZ-14525R
英文名称EHD1
中文名称EHD1蛋白抗体
别 名CDABP0131; EH domain containing 1; EH domain-containing protein 1; EHD1; EHD1_HUMAN; FLJ42622; FLJ44618; H PAST; hPAST1; PAST; PAST homolog 1; PAST1; Testilin.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 信号转导 生长因子和激素 新陈代谢
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow,
EHD1蛋白抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量61kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human EHD1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
EHD1蛋白抗体PubMedPubMed
产品介绍background:
This gene belongs to a highly conserved gene family encoding EPS15 homology (EH) domain-containing proteins. The protein-binding EH domain was first noted in EPS15, a substrate for the epidermal growth factor receptor. The EH domain has been shown to be an important motif in proteins involved in protein-protein interactions and in intracellular sorting. The protein encoded by this gene is thought to play a role in the endocytosis of IGF1 receptors. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]

Function:
Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes.

Subunit:

Subcellular Location:
Cell membrane. Early endosome membrane. Recycling endosome membrane. Associated with intracellular tubulovesicular structures.

Tissue Specificity:
Highly expressed in testis.

Post-translational modifications:

EHD1蛋白抗体Similarity:
Contains 1 EF-hand domain.
Contains 1 EH domain.

Gene ID:
10938

Database links:
Entrez Gene: 10938 Human
Entrez Gene: 13660 Mouse
Entrez Gene: 293692 Rat
Omim: 605888 Human
SwissProt: Q9H4M9 Human
SwissProt: Q9WVK4 Mouse
SwissProt: Q641Z6 Rat
Unigene: 523774 Human
Unigene: 710868 Human
Unigene: 30169 Mouse
Unigene: 471458 Mouse
Unigene: 8141 Rat

EHD1蛋白抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.