Iterative Crystallography Service：Bisphosphoglycerate mutase
产品名称： Iterative Crystallography Service：Bisphosphoglycerate mutase
英文名称： Iterative Crystallography Service：Bisphosphoglycerate mutase
产品编号：
产品价格： 询价
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http://www.creative-biostructure.com/Iterative-crystallography/Iterative-crystallography-CBCRY13.htm
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Cat. No. |
CBCRY13 |
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Background |
Bisphosphoglycerate mutase is an erythrocyte-specific enzyme catalyzing a series of intermolecular phosphoryl group transfer reactions. Its main function is to synthesize 2,3-bisphosphoglycerate, the allosteric effector of hemoglobin. |
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Molecular description |
Protein Classification |
Isomerase |
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Structure Weight |
63399.57 Da |
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Polymer |
1 |
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Molecule |
Bisphosphoglycerate mutase |
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Chain Length |
271 amino acids |
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Crystal Description |
PDB ID |
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MMDB ID |
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Source |
E.coli |
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Method |
X-Ray Diffraction |
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Resolution |
1.5 Å |
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Ligand Chemical Component |
3-phosphoglyceric acid; 2,3-diphosphoglyceric acid; cyclohexylammonium ion |
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Gene information |
Gene Name |
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Synonyms |
EC 5.4.2.4; EC 5.4.2.1; EC 3.1.3.13; 2,3-bisphosphoglycerate mutase; 2,3-bisphosphoglycerate mutase, erythrocyte; 2,3-bisphosphoglycerate synthase; BPG-dependent PGAM |
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UniProt ID |
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GeneID |
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Chromosome Location |
7q31-q34 |
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Function |
bisphosphoglycerate 2-phosphatase activity; bisphosphoglycerate mutase activity; hydrolase activity; isomerase activity; phosphoglycerate mutase activity; intramolecular transferase activity; phosphatrasferase |
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Reference |
Wang, Y., Liu, L., Wei, Z., Cheng, Z., Lin, Y., Gong, W. (2006) Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase. J.Biol.Chem. 281: 39642-39648 |
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